Test Management Tools are very important for effectively managing your Requirements, Test case preparation & execution and Bug reporting.
There are many Test Management Tools available on the market, a few example of which include HP Quality Center and IBM Rational Quality Manager.
HP Quality Center is sold as a web based Tool, but in order to allow users to access it from the web browser, it needs to be installed in an in-house server. Quality Center also requires installing some ActiveX controls in the Client machines.
Setting up and using HP Quality Center requires some skill. I often get requests asking for guidance to set up Quality Center. In fact there are a number of courses on offer aimed solely at teaching people how to use Quality Center. Additionally, the price of Quality Center used to be high.